ShinyGO: a graphical gene-set enrichment tool for animals and plants

ShinyGO is an intuitive graphical web application built to help researchers interpret the gene lists routinely produced by genome-wide studies. It performs enrichment analysis to link those lists with underlying molecular pathways and functional categories such as gene ontology, drawing on a large annotation database derived from Ensembl and STRING-db that spans 59 plant, 256 animal, 115 archaeal, and 1678 bacterial species.

Its distinguishing features are graphical visualization of enrichment results and gene characteristics, along with application programming interface access to KEGG and STRING for retrieving pathway diagrams and protein-protein interaction networks. By combining broad species coverage with visualization and external database integration, ShinyGO helps researchers gain actionable insights from their gene lists.